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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
10.91
Human Site:
S596
Identified Species:
17.14
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S596
K
E
D
E
S
E
K
S
Y
E
N
V
D
S
G
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S596
K
E
D
E
S
E
K
S
Y
E
N
V
D
S
G
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
S348
P
Q
T
A
V
G
P
S
H
P
A
W
V
P
A
Dog
Lupus familis
XP_534537
1097
121903
Q583
G
K
D
K
K
Q
I
Q
T
S
P
V
P
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S595
K
E
D
D
S
E
K
S
A
D
S
G
D
S
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
H587
D
E
E
G
E
K
T
H
D
N
F
D
S
G
D
Chicken
Gallus gallus
XP_419666
1136
127431
N602
K
E
E
E
N
E
K
N
Y
E
C
V
D
S
A
Frog
Xenopus laevis
NP_001087838
1118
125984
T591
I
E
A
T
T
G
I
T
E
K
K
Q
I
T
T
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
F582
S
P
Q
A
F
K
F
F
M
E
Q
H
V
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
P585
A
T
T
P
P
I
P
P
A
K
Y
N
N
N
S
Honey Bee
Apis mellifera
XP_395146
1137
124999
G632
S
P
D
N
G
A
K
G
A
G
S
S
P
S
S
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
K15
M
E
I
S
Q
Y
T
K
D
K
A
S
C
T
R
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
E672
I
S
D
V
G
D
L
E
S
A
S
S
D
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
Q295
L
K
I
E
N
F
Y
Q
S
S
V
K
Y
A
I
Red Bread Mold
Neurospora crassa
P38679
598
67999
K137
A
P
E
R
N
P
D
K
Y
G
P
N
A
N
N
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
13.3
N.A.
66.6
N.A.
N.A.
6.6
66.6
6.6
6.6
N.A.
0
20
6.6
20
P-Site Similarity:
100
100
20
33.3
N.A.
86.6
N.A.
N.A.
20
86.6
33.3
13.3
N.A.
20
26.6
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
14
0
7
0
0
20
7
14
0
7
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% C
% Asp:
7
0
40
7
0
7
7
0
14
7
0
7
34
0
7
% D
% Glu:
0
47
20
27
7
27
0
7
7
27
0
0
0
7
0
% E
% Phe:
0
0
0
0
7
7
7
7
0
0
7
0
0
0
0
% F
% Gly:
7
0
0
7
14
14
0
7
0
14
0
7
0
7
20
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
7
0
0
0
% H
% Ile:
14
0
14
0
0
7
14
0
0
0
0
0
7
0
7
% I
% Lys:
27
14
0
7
7
14
34
14
0
20
7
7
0
0
0
% K
% Leu:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
20
0
0
7
0
7
14
14
7
14
14
% N
% Pro:
7
20
0
7
7
7
14
7
0
7
14
0
14
7
0
% P
% Gln:
0
7
7
0
7
7
0
14
0
0
7
7
0
0
7
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
14
% R
% Ser:
14
7
0
7
20
0
0
27
14
14
20
20
7
40
14
% S
% Thr:
0
7
14
7
7
0
14
7
7
0
0
0
0
14
7
% T
% Val:
0
0
0
7
7
0
0
0
0
0
7
27
14
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
7
7
0
27
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _